You’ve been rushing through the grocery store for an hour already. Your kids have thrown multiple unnecessary items in to the cart. You’re famished, frazzled, and finally ready to check out.
Then you remember: You’re in dire need of toothpaste. That crumpled tube on the bathroom counter at home continues to be squeezed to its limit, and you’re certain that not even the tiniest speck of paste might be further extracted.
The problem is, when you arrive in the toothpaste aisle, you’re not exactly sure what to choose.
Whiter! Brighter! Fresher breath! These empty promises and more scream at you from fancy packaging, and while you may be distracted by all that marketing jargon, it’s important to know that it’s what’s within those packages that actually counts. Works out, there are a lot of superfluous — and dangerous — chemicals in toothpaste.
Many conventional toothpastes contain harmful ingredients can be difficult to recognize on the label. Below I’ve outlined which of these ingredients are harmful and why you need to opt for nontoxic toothpaste. (I’ve also designed a downloadable version of this list so you can print it out or save it to your phone and take it along with you anywhere.)
Do a Toothpaste’s Ingredients Really Matter If I’m Not Swallowing It?
You may be wondering why avoiding toxic toothpaste ingredients is really important when toothpaste isn’t in your mouth for very long, and even when it is, you certainly don’t swallow it.
But here’s the deal: The mouth-body connection is very real, and bad oral health can contribute to heart disease, diabetes, osteoporosis, along with other conditions. As a result, having a healthy mouth is paramount, and anything we put into our mouths — no matter how briefly — can impact our oral and overall health.
Our mouths are lined with protective mucous membranes, which could become irritated, inflamed, and infected with toxic ingredients. Our mouths may also absorb those chemicals in to the bloodstream, while certain ingredients can disrupt the natural balance of flora (both “good” and “bad” bacteria) within our mouths that aids in maintaining our dental health. This imbalance can even affect your gut microbiome.
Here’s a closer look at some of the most concerning toothpaste additives:
- Titanium Dioxide (TiO2)
What it's: Titanium dioxide is an inorganic chemical compound added like a colorant to make toothpaste white.
Why it’s harmful: While most research has concluded that titanium dioxide is safe for topical use on skin since it isn’t absorbed, there haven’t been studies to determine if it is absorbed by the mucous membranes within the mouth. According to the Environmental Working Group, there's concern about inhalation of titanium dioxide, because it may be carcinogenic and could cause nonreproductive-organ-system toxicity.
It’s also important to note that titanium dioxide doesn’t provide any oral benefit; it’s simply a part of a marketing tactic to appeal to people who like brilliantly white toothpaste.
What it's: Triclosan is a pesticide added to many consumer products as an antibacterial agent.
Why it’s harmful: There have been numerous animal studies which have linked triclosan to endocrine (hormone) disruption. It could also contribute to creating antibiotic-resistant strains of bacteria.
And think about this: The FDA has banned the use of triclosan in soap and body wash (but approves it for use in toothpaste). In my opinion, this is proof enough of the dangers of triclosan. Why would I put something in my mouth that I wouldn’t put on my hands?
- Sodium lauryl sulfate (SLS)
What it is: SLS is a chemical compound used as a surfactant, detergent, and denaturant in various cosmetics and industrial cleaners. It’s also used like a foaming agent in toothpaste.
Why it’s harmful: Almost 16,000 studies have mentioned the toxic nature of SLS, yet it is still used in many cosmetic products, in addition to most conventional toothpastes. EWG maintains that this chemical, which is also used as an insecticide, can cause irritation and organ toxicity. SLS irritates the mouth and strips away the lining, which can lead to canker sores.
Be careful when you’re looking for this dangerous, and sneaky, chemical in toothpaste ingredient lists. Manufacturers often list SLS by other names, including:
- Sodium dodecyl sulfate (SDS)
- Monododecyl ester
- Sodium salt
- Sulfuric acid
- Sodium salt sulfuric acid
- Monododecyl ester sodium salt sulfuric acid
- Sulfuric acid monododecyl ester sodium salt
- Aquarex methyl
- Akyposal SDS
What it's: Fluoride is a chemical added to prevent cavities by aiding remineralizing of tooth structure.
Why it’s harmful: There’s grounds all fluoride-containing products come with an FDA warning: According to the Fluoride Action Network, even small amounts of fluoride can cause acute toxicity, seen as a nausea, vomiting, and headaches in the earliest stages. But the most shocking news about fluoride has become the fact that no over-the-counter toothpaste formula contains enough of the substance to actually remineralize teeth, and manufacturers can’t increase the because of FDA regulation.
Too much fluoride can also harm developing teeth in young children, who tend to swallow many of the toothpaste they’re using, leading to fluorosis, among other issues. Also, in order for topical applications of fluoride to be effective, it must be put on the teeth after brushing so the biofilm is removed and fluoride can be absorbed. (FYI: I do recommend fluoride in certain circumstances but not in over-the-counter toothpastes, as the risk-reward ratio just doesn’t make sense.)
- Artificial coloring
What it is: Artificial toothpaste colors are used to make commercial toothpaste aesthetically pleasing.
Why it’s harmful: Studies have linked artificial coloring chemicals to hyperactivity and ADHD in youngsters; in fact, a study published in 2012 by Neurotherapeutics found that artificial food colors may have a negative effect on children even if they haven’t been diagnosed with ADHD. I don’t know about you, but I’m much more worried about how effective my toothpaste is, not how sparkly and blue it is.
- Abrasive ingredients
What they are: Abrasive ingredients are added to toothpaste to help “scrub” biofilm from the teeth.
Why it’s harmful: Toothpaste only must be mildly abrasive to be effective. Some of the abrasives used, such as hydrated silica, are extremely rough. These ingredients can remove the enamel and dentin, creating sensitivity and resulting in gum recession.
What they are: Parabens are chemicals used as preservatives to extend the shelf life of the toothpaste.
Why it’s harmful: The FDA continues to be reviewing and evaluating published studies around the safety of parabens. Recognized to disrupt hormones, parabens are utilized in most cosmetic products and even in most grocery items. Even if the levels in these individual goods are considered “safe,” the accumulation in our bodies could cause problems, together with a possible increase in the risk of cancer of the breast.
- Propylene Glycol
What it is: Propylene glycol is a synthetic chemical compound used like a surfactant.
Why it’s harmful: Although the FDA classifies propylene glycol as GRAS (generally acknowledged as safe), this compound may irritate the skin, eyes, lungs, and mucous membranes. Case in point: the industrial-grade form is used in antifreeze, detergent solvents, and paint. According to research showing that propylene glycol was toxic in rats after long-term use, authors of a 2021 study advised that intake of propylene glycol (and artificial colors, incidentally) be limited, particularly in children.
- Saccharin (Sodium Saccharin)
What it is: Saccharin is an artificial sweetener used as a flavoring agent.
Why it’s harmful: Saccharin is really a known carcinogen in rats, and although it hasn’t been shown to cause the same type of cancer in humans, I’m uncomfortable with it being added to my toothpaste for that sole purpose of making it more palatable. Also, it can cause coughing, nausea, vomiting, and diarrhea.
What it is: Carrageenan in toothpaste should be avoided. Carrageenan is really a food additive extracted from red seaweed (also known as Irish moss) and used as a thickener.
Why it’s harmful: Carrageenan has created intestinal issues, including inflammation and colon ulcerations, in certain animal studies. Many people have reported intestinal distress that is resolved with the avoidance of carrageenan products. Additionally, the degraded form is really a known carcinogen. During processing, the undegraded (food-grade) form may be easily contaminated through the degraded form.
What it is: Aspartame is definitely an artificial sweetener used as a flavoring agent.
Why it’s harmful: When aspartame is ingested, one of the chemicals in the compound is divided into methanol, an alcohol. Our bodies cannot properly digest it within this form. It can travel through the blood and could be converted into formaldehyde. As this accumulates in the body, the damage caused can include headaches, dizziness, weakness, loss of memory, and gastrointestinal distress. A 2021 study also determined that aspartame is really a possible carcinogen.
- Diethanolamine (DEA)
What it is: DEA is really a chemical used as a foaming agent in toothpastes.
Why it’s harmful: This compound is yet another known hormone disruptor, and the EWG ranks it in a full 10 on its hazard scale. It’s also used in some products to adjust the pH levels and may react with certain substances to produce carcinogens. If that weren’t enough, DEA is known to cause organ-system toxicity.
Making Your Own Toothpaste
Unfortunately, avoiding these harsh chemicals can be difficult. Again, I recommend downloading their list of the most harmful toothpaste ingredients, but when you want to be extra careful, I recommend taking a DIY approach. Making your own toothpaste isn’t foolproof, however, as I’ve seen DIY recipes that are just as harsh as mainstream toothpaste.
Start with my Complete Help guide to DIY Toothpaste to learn more about which ingredients are wonderful to use, and which ones ought to be left out when you’re mixing your own blend. (And if you’re curious, here’s the precise recipe I use to make my own toothpaste at home.)
This article has been updated. It was originally published March 20, 2021.